The best health & wellness spots in De Soto

20 health & wellness spots we’ve checked and stand behind — with the story on each one. Not a ranking; a record.

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Health & Wellness · 20 places · showing the latest additions first

Jefferson County YMCA

Health & Wellness

Community-focused nonprofit established in 1844 with recreational programs & services for all ages.

1303 YMCA Dr (Festus)

Community-focused nonprofit established in 1844 with recreational programs & services for all ages.

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FlexTime Fitness

Health & Wellness

FlexTime Fitness pairs trainer guidance with a straightforward setup, from training to corporate wellness, and you can request appointments…

1401 S Brentwood Blvd #135 (St. Louis)

FlexTime Fitness pairs trainer guidance with a straightforward setup, from training to corporate wellness, and you can request appointments online. If you’re in University City and want a no-nonsense place to make a routine stick, this is it.

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Blue Sky Yoga St. Louis

Health & Wellness

Blue Sky Yoga St. Louis keeps things welcoming for every level with thoughtfully taught classes, community workshops, and a Yoga Alliance…

3525 Watson Rd (St. Louis)

Blue Sky Yoga St. Louis keeps things welcoming for every level with thoughtfully taught classes, community workshops, and a Yoga Alliance certified 200 hour teacher training in the heart of St. Louis.

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Community-focused nonprofit established in 1844 with recreational programs & services for all ages.

605 Locust St (St. Louis)

Community-focused nonprofit established in 1844 with recreational programs & services for all ages.

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Jennings Community Center

Health & Wellness

When you want a no-frills place to get moving, skip the chain gyms and check out Jennings Community Center. Solid workout options,…

2315 Ada Wortley Ave (St. Louis)

When you want a no-frills place to get moving, skip the chain gyms and check out Jennings Community Center. Solid workout options, neighborly energy, and the kind of community vibe that makes sticking with a routine feel less like a chore and more like catching up.

From the Florissant newsletter, September 11, 2026

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PRICK'D Medspa

Health & Wellness

PRICK'D Medspa calls itself St. Louis’s first Skin + Injectables Bar, pairing evidence-based care with a social vibe across Botox, fillers,…

35 The Blvd Saint Louis (St. Louis)

PRICK'D Medspa calls itself St. Louis’s first Skin + Injectables Bar, pairing evidence-based care with a social vibe across Botox, fillers, Kybella, lasers, Hydrafacial, microneedling, and IV drips. It’s fast, polished, and results-forward, which is exactly what your week needs between Schnucks runs and Zoom calls.

From the University City newsletter, September 15, 2026

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Aquarius Wellness Center For Healing Arts and Spa is a boutique day spa that leans into the quiet stuff, restorative massage, facials,…

7750 Clayton Rd Suite 103 (St. Louis)

Aquarius Wellness Center For Healing Arts and Spa is a boutique day spa that leans into the quiet stuff, restorative massage, facials, Reiki, and waxing, plus couples packages with warm stones, reflexology, and treats like a mini champagne and Swiss chocolates. When your week overdoes it, this place resets.

From the University City newsletter, September 10, 2026

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Titanium Fitness

Health & Wellness

Whether you want one-on-one coaching, tag-team Dual Training with a buddy, or a small group vibe that keeps you honest, Titanium Fitness…

854 Hanley Industrial Ct (St. Louis)

Whether you want one-on-one coaching, tag-team Dual Training with a buddy, or a small group vibe that keeps you honest, Titanium Fitness builds individualized plans with real accountability and a friendly, non-intimidating community.

From the St. Louis newsletter, September 16, 2026

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Day spa offering massage therapy, acupuncture, and CBD skincare.

7200 Manchester Rd (St. Louis)

Day spa offering massage therapy, acupuncture, and CBD skincare.

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Given100

Health & Wellness

Whether your kid is chasing varsity minutes or you're dusting off the old cleats, Given100 builds real athletic foundations with sports…

5648 Pershing Ave (St. Louis)

Whether your kid is chasing varsity minutes or you're dusting off the old cleats, Given100 builds real athletic foundations with sports performance and personal training that actually translate on the field.

From the University City newsletter, September 13, 2026

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Bayer YMCA

Health & Wellness

Community-focused nonprofit established in 1844 with recreational programs & services for all ages.

5555 Page Blvd (St. Louis)

Community-focused nonprofit established in 1844 with recreational programs & services for all ages.

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From acupuncture and craniosacral therapy to massage, intuitive readings, nutrition coaching, and energy therapy, The Center For Mind Body…

7649 Delmar Blvd (St. Louis)

From acupuncture and craniosacral therapy to massage, intuitive readings, nutrition coaching, and energy therapy, The Center For Mind Body & Spirit tailors holistic care to what you actually need.

From the St. Louis newsletter, September 13, 2026

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Whether you're easing back from an injury or just want to keep up with the grandkids, Lionheart Personal Training focuses on smart strength…

1039 S Big Bend Blvd (St. Louis)

Whether you're easing back from an injury or just want to keep up with the grandkids, Lionheart Personal Training focuses on smart strength work for every level, especially middle age and senior fitness.

From the St. Louis newsletter, September 3, 2026

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Pure Hot Yoga St. Louis

Health & Wellness

Studio with a warm vibe for hot yoga and pilates classes, featuring knowledgeable and friendly instructors.

6630 Clayton Rd (St. Louis)

Studio with a warm vibe for hot yoga and pilates classes, featuring knowledgeable and friendly instructors.

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Grand Basin Yoga

Health & Wellness

Grand Basin Yoga is a private studio in a public setting at Forest Park, led by trauma informed integrative wellness specialist Dianna…

Lagoon Dr (St. Louis)

Grand Basin Yoga is a private studio in a public setting at Forest Park, led by trauma informed integrative wellness specialist Dianna Lucas. Expect thoughtful yoga, guided meditation, sound work, and sacred ceremonies, plus 19 years of community roots... solid for neighbors craving grounded movement without the scene.

From the University City newsletter, September 9, 2026

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Celsius Med Spa STL

Health & Wellness

Celsius Med Spa STL keeps it real with customized noninvasive treatments that enhance what you already have, perfect for a midweek reset.…

1760 S Brentwood Blvd (St. Louis)

Celsius Med Spa STL keeps it real with customized noninvasive treatments that enhance what you already have, perfect for a midweek reset.

From the St. Louis newsletter, August 4, 2026

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Central Studio

Health & Wellness

Central Studio is where St. Louis keeps its groove, with flexible drop-in adult dance classes from tap and hip hop to ballet and aerial…

5617 Pershing Ave (St. Louis)

Central Studio is where St. Louis keeps its groove, with flexible drop-in adult dance classes from tap and hip hop to ballet and aerial plus upbeat, no-experience-needed fitness. Want something more mindful?

From the St. Louis newsletter, August 20, 2026

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Bravo Shape STL

Health & Wellness

Bravo Shape STL stacks pro-grade, non-invasive tech like CryoSculpting and Contour Light into personalized protocols that target fat, skin,…

10511 Old Olive Street Rd (St. Louis)

Bravo Shape STL stacks pro-grade, non-invasive tech like CryoSculpting and Contour Light into personalized protocols that target fat, skin, and muscle for compounding results. Think inches lost in as few as 3 sessions, zero downtime, and sessions that actually fit your week, not wreck it.

From the Chesterfield newsletter, August 22, 2026

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Yes Honey Studio

Health & Wellness

Yes Honey Studio mixes dance fitness, yoga, barre, and strength training in a renovated studio in The Grove led by world-class instructors.…

Retail South, 1519 Tower Grove Ave (St. Louis)

Yes Honey Studio mixes dance fitness, yoga, barre, and strength training in a renovated studio in The Grove led by world-class instructors. It’s sweaty, upbeat, and actually fun, with group sessions, private lessons, and pop-up Honey Happenings that keep your week feeling fresh instead of same-old.

From the St. Louis newsletter, August 27, 2026

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If your hips and hamstrings are protesting, Stretch U & Cryotherapy - Rock Hill pairs one on one assisted stretching with PNF and…

9426 Manchester Rd (St. Louis)

If your hips and hamstrings are protesting, Stretch U & Cryotherapy - Rock Hill pairs one on one assisted stretching with PNF and myofascial release to loosen you up. Cap it with a quick cryotherapy session to cool inflammation and bounce back for your next run, lift, or long desk day.

From the St. Louis newsletter, August 20, 2026

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