Best Med Spas in Sioux Falls, SD


Refined Aesthetics
With a focus on enhancing natural beauty, Refined Aesthetics specializes in advanced aesthetic treatments tailored to individual skin goals. Clients benefit from procedures such as Radio Frequency Microneedling, PRP therapy, wrinkle relaxers, and dermal fillers, all performed by highly qualified professionals. Their patient-centered approach includes complimentary initial consultations, ensuring personalized care plans and thorough education on treatment options. The welcoming environment, state-of-the-art technology, and use of FDA-approved products make this practice an appealing choice for anyone seeking safe and effective results.


JMISKO surgical design | md
If you’re considering a full-service med spa that covers everything from Botox and fillers to advanced hair restoration and hormone therapy, JMISKO surgical design | md stands out for its variety and expertise. Clients appreciate the tailored treatment plans and flexible appointment options, making it convenient for busy schedules. Led by Dr. Justin Misko, a seasoned hair loss specialist, this practice draws praise for professionalism and noticeable results. Special promotions pop up regularly, and their top-tier status with Allergan boosts confidence in their services. It’s a great choice for anyone seeking comprehensive, personalized aesthetic care.


Serenity Spa & Facials
With a focus on non-surgical, professional skincare, Serenity Spa & Facials specializes in rejuvenating facial and body treatments using advanced anti-aging technologies inspired by Nobel Prize-winning research. Clients enjoy a wide menu, including LED Light Facials, HydroFacials, and luxurious 24K Gold Treatments, all personalized for unique skin needs. Their excellent team of licensed estheticians and use of natural products help create visible results without harsh chemicals or downtime. Flexible hours and perks like a $99 voucher or Gold Membership make Serenity Spa a compelling choice for those seeking long-lasting radiance and pampering.
Novo Aesthetics

Novo Aesthetics offers a comprehensive menu of medical spa services, specializing in anti-wrinkle injections, dermal fillers, chemical peels, microneedling with PRP, and personalized weight loss programs using semaglutide and tirzepatide. Led by seasoned professionals, they focus on tailored plans, minimal downtime, and natural-looking results, making it easy to feel confident about your care.
Liv Med Spa | Sioux Falls, SD

Committed to empowering confidence through personalized care, Liv Med Spa specializes in advanced aesthetic and wellness treatments tailored to each client. Their standout offerings include medical weight loss with GLP-1 medications, state-of-the-art laser tattoo removal, microneedling, and exclusive membership perks. Flexible payment options, expert clinical leadership, and attentive consultations make it a smart choice for those seeking expertise and natural-looking results.
Artisan Skin and Laser Center

Surrounded by a calming atmosphere and expert care, Artisan Skin and Laser Center stands out for personalized non-invasive treatments like laser resurfacing, injectables, and customized skincare plans. Overseen by Dr. Alison R. Tendler, the experienced team blends science and artistry using the latest technology, with special discounts for new clients seeking long-lasting, visible improvements in skin health.
Infinity Medical Aesthetics

Infinity Medical Aesthetics delivers a full spectrum of medical spa services, specializing in injectables, advanced skin treatments, body contouring, and medical weight loss. With a luxurious atmosphere, in-room checkout, and private exits, clients enjoy comfort and privacy. Staffed by licensed professionals, treatments use trusted brands and the latest laser technology for personalized, high-quality results. New patients enjoy attractive promotions.
Lazaderm – Sioux Falls

Lazaderm – Sioux Falls specializes in advanced skin and body rejuvenation, focusing on non-surgical solutions like laser hair removal, microneedling, CoolSculpting Elite, cosmetic injectables, and more. Backed by experienced medical professionals and led by Dr. Lornell Hansen II, Lazaderm offers free consultations, personalized plans, and flexible financing in a comfortable, patient-focused environment with consistently strong client reviews.
Chapter Aesthetic Studio

Feeling at ease from the moment you walk in, Chapter Aesthetic Studio stands out for its highly trained team and thorough MAP process, which crafts a custom plan for every client. Specializing in everything from Botox and fillers to CoolSculpting and medical-grade facials, they offer transparent pricing, exclusive online deals, and free consultations to ensure each experience is welcoming and results-focused. (63 words)
Kalon Medical Spa
Stepping into Kalon Medical Spa means enjoying advanced treatments like Sciton JOULE X laser, customized facials, fillers, and noninvasive body sculpting, all led by expert providers who blend genuine care with truly personalized results.
LIVE Hydration Spa – Sioux Falls, SD
LIVE Hydration Spa specializes in IV hydration therapy, vitamin injections, and Botox, with treatments performed by registered nurses under physician supervision. Clients appreciate the relaxing atmosphere, flexible hours, and custom therapies tailored to individual wellness goals.
Legacy Med Spa
Legacy Med Spa specializes in aesthetic and wellness services like cosmetic injectables, weight loss programs, and IV therapy, combining 25 years of expertise with truly personalized care in a welcoming, modern setting focused on natural results and client satisfaction.
Serenity Spa & Facials Sioux Falls at Marion Road
Offering advanced facial treatments and body contouring, Serenity Spa & Facials stands out for personalized care, experienced estheticians, and a relaxing atmosphere, with special deals making professional skincare feel accessible and results-driven for all clients.
Etched Medical Spa
Covering everything from cosmetic to medical Botox, Etched Medical Spa specializes in mobile treatments brought directly to you. Personalized consultations and flexible scheduling make it perfect for those valuing convenience, professionalism, and a tailored approach.
KJ Relaxin Medical Spa
Believing in accessible wellness, KJ Relaxin Medical Spa stands out with FSA- and HSA-eligible treatments, a custom skin care line, flexible hours, and options like facials, injectables, and body sculpting delivered by certified professionals.
Lisa’s Lil Spa Room
Lisa’s Lil Spa Room offers facials, lash lifts, sugaring, body contouring, and IV therapy, specializing in tailored treatments with advanced techniques. Clients enjoy a personalized touch, licensed expertise, ongoing specials, and consistently praised, attentive service.
Vivaz Medical Spa
Vivaz Medical Spa delivers advanced skin rejuvenation and anti-aging services by experienced Sanford Health professionals, offering personalized treatments like HydraFacials, injectables, and laser therapies in a medical-grade environment with flexible appointment options and seasonal product discounts.
How Power Rankings Work
– Medical credentials and staff certifications
– Equipment quality and FDA approvals
– Treatment diversity (injectables, laser, body contouring)
– Safety and sterilization protocols
– Facility comfort and layout
– Transparent pricing and package options
– Post-treatment follow-up and care
– Consistency of client outcomes
Pro tip: Before you book, list your must-have services—whether it’s microneedling, filler, or laser resurfacing—and compare each spa’s post-care support and package flexibility to make sure your treatment plan goes off without a hitch.