There’s something special about the search for the perfect slice … crispy crust, melty cheese, and all the creative toppings that make every pie a new adventure. Fort Myers has no shortage of pizzerias, from family-run diners to trendy craft spots, each serving up their own spin on this classic favorite.
Let’s get to it.
Pizza @ 41
When you’re craving straightforward pizza without frills, Pizza @ 41 delivers. This neighborhood spot sits in a retail strip on Cleveland Avenue. The space is compact, with limited tables, so most guests grab an order to go or choose delivery. They serve from 10 AM until 9:50 PM, covering midday lunches and late dinner runs.
The menu focuses on American-Italian, hand-tossed pies with a medium crust. Classic choices include Meat Lover, Chicken Bacon Ranch, BBQ Chicken and Papa Pepperoni. Vegans will find a veggie pie, and there’s even a Buffalo Chicken option for a spicy kick. Prices range from $12 to $27. Subs, sides and cookies all cost under $10, and buy-one-get-one deals make sharing easy. Wings and hot or cold subs add variety for anyone in a non-pizza mood.
Counter service, curbside pick-up and delivery are the rules here. You won’t find candlelit tables, just reliable pizza ready when you need it. No tablecloths, no neon art, just pizza that arrives hot.
3 City Pizzeria
Located off McGregor Boulevard, 3 City Pizzeria serves three regional styles of pizza from Chicago, New York, and Detroit. The Chicago thin-crust pie arrives cracker-crisp and is cut into squares. Fans of bold flavors go for the Italian Beef Pizza topped with hot giardiniera peppers. The New York-style Margherita delivers classic mozzarella, tomato, and basil, while the Ultra Pepperoni piles on double pepperoni and a sweet hot honey drizzle.
Pies like The Gumba carry a meat lover’s lineup of pepperoni, sausage, ham, and bacon. All dough and sauces are made in-house, keeping prices between thirteen and twenty dollars. That range feels fair for scratch-made ingredients.
Inside, seating is limited so large groups may need to split up, but the pet-friendly patio welcomes dogs. Counter service provides quick pickup and servers often chat about family recipes passed down through generations. Beyond pizza, they offer subs, calzones, and cannoli. A small craft beer fridge rotates local and regional brews. For its home neighborhood, 3 City Pizzeria punches above its weight in both variety and quality.
Vincenzo’s Pastaria
Since opening in 2006, Vincenzo’s Pastaria has offered New York-style pizza and classic pastas in Fort Myers. Every pizza features hand-tossed, thin-crust dough available in 14-inch or 18-inch sizes. Favorites include the simple cheese pie, the white pizza topped with mozzarella and ricotta, and the Quattro Formaggio loaded with gorgonzola and pecorino.
Toppings range from pepperoni and sausage to broccoli, sun-dried tomatoes, and anchovies. Each specialty pizza is finished with a drizzle of extra-virgin olive oil and fresh garlic. Homemade dough and high-quality cheeses set the tone.
The bright dining room fits about thirty guests beneath a photo gallery that celebrates local families and long-time patrons. Counter service keeps lunch lines moving, and the slice-and-soda special for eight dollars draws office crowds. Beyond pizza, the menu lists stromboli, heroes, baked pastas, and salads. Patrons can dine in, pick up takeout, or schedule delivery. With simple decor, friendly staff, and neighborhood prices, Vincenzo’s Pastaria delivers reliable Italian comfort food every day.
Lombardough’s Pizza & Beer
Walking into Lombardough’s Pizza & Beer on South Tamiami Trail, you see local murals and a blend of a backyard vibe with a craft beer hangout. The menu focuses on Neapolitan-style, wood-fired pizzas with a chewy crust that pairs well with a cold pint.
They use a dough-stretching robot for consistency, then top pies like the Roasted Veggie with artichoke hearts and balsamic, the Buffalo Bill with blue cheese drizzle, or the Spicy Hawaiian with bacon and jalapeño. The meatball pizza arrives on a garlic-infused crust.
Outside, patio lights hang over cornhole boards. Live guitar sets fill the air while dogs and kids roam. Owners Corbin Nicholl and Matt Lombardo—who first collaborated on landscaping—designed the space themselves. You order at self-service kiosks or a counter window, then choose from rotating local beers or try a kava seltzer. Prices match the craft-pizza scene and allow build-your-own pies. The relaxed layout and varied seating mean you never feel rushed. This isn’t just another patio, it’s a place with its own strong sense of style.
McGregor Pizza & Deli
At McGregor Pizza & Deli, neighborhood flavor meets a variety of options on McGregor Boulevard. Locally run by Katie Madden Marciano since 2017, this pizzeria offers New York-style brick-oven pizzas with hand-tossed, thin-crust, gluten-free or plant-based bases. The build-your-own “Pizza Your Way” lets diners choose up to five toppings. Signature pies include Margherita with fresh basil and mozzarella, or Katie’s Mediterranean with spinach, tomato and feta.
Garlic knots arrive hot from the oven, and pepperoni popper knots add a cheesy, spicy twist. Deli favorites like Italian heroes, calzones and strombolis sit alongside sides such as wings and salads. Pricing ranges mostly from $12 to $23 per pizza, and moderate rates make group orders easy.
Inside seating welcomes about 50 guests, with an outdoor patio space for pets. Late-night hours serve late cravings, and text-club deals or fundraisers offer occasional discounts. A generous parking lot and street spots make pick-up simple. Whether you stop in for lunch or order delivery after hours, McGregor Pizza & Deli delivers straightforward flavors and a family-friendly vibe.
Uncle Rico’s Pizza Fort Myers
At Uncle Rico’s Pizza Fort Myers, New York-style slices and square Sicilians share top billing on Cleveland Avenue. Counter service keeps things easy, place an order then wait through the toppings list. The “Angry Uncle” pie arrives with hot honey drizzle. The House Special layers sausage, peppers, mushrooms and pepperoni on a classic crust. Cauliflower crust is also on the menu for those avoiding wheat.
Owner Enrico Aguila has been perfecting pies for over twenty years. He built his reputation by turning out as many as 400 pies in a single day. Beyond pizza, diners find hearty options like beef patties, calzones and a selection of desserts including tiramisu and cheesecake.
The appointment-only Grandma Crust requires advanced notice since the dough needs extra prep time. Prices stay reasonable whether you order a single slice or a whole pie. A cheeseboard option starts at $16, adding a meaty snack to any order. Seating is casual, so most guests pick up or order delivery. No fancy decor here, just solid pizza and straightforward service on Cleveland Avenue.
Fine Folk Pizza
Tucked in a Fort Myers strip plaza, Fine Folk Pizza balances neighborhood-casual comfort with inventive flavors. Founded in 2015 by a local family, this joint specializes in New York-style pies. The 72-hour cold ferment gives the crust a rich taste and chewy texture.
You won’t find standard pepperoni-only pies here. The Krab Rangroovin features scallion cream cheese, crispy Asian noodles and spicy mayo. The Yo Johnny pairs cup-and-char pepperoni with hot honey. Vegan eaters can order menu items like It’s a Philly Thing, loaded with vegan cheese, portobello mushrooms and pretzel croutons. Gluten-free and cauliflower crust options are also available.
Inside, seating is limited, but there’s a small patio for warmer days. Staff throw dough behind the counter and perform certified acrobatics that keep kids and adults entertained. Lunch rushes fill the space with hungry diners drawn by effort-packed pies that range from $11 to $17. Delivery and pickup services cover the wider Fort Myers area. For home chefs, Take-Home Pizza Kits include pre-portioned dough, sauce and cheese, so you can recreate the experience in your own kitchen.
Downtown House of Pizza
Since 2005, Downtown House of Pizza has welcomed diners in the Fort Myers River District. The menu centers on hand-tossed, New York-style pies with large, foldable slices served from the counter. A square Sicilian “Grandma’s” pie offers a thinner crust packed with toppings. They also offer gluten-free and cauliflower crusts, plus vegan cheese for dairy-free diets.
Inside, guests claim spots at communal tables or outdoor patio seating on Hendry Street. On busy nights families, music lovers and locals share the space. A selection of local and national beers pairs well with pizza slices. Prices stay moderate, with a combo of a thick slice and a drink that won’t hurt the wallet.
Subs, strombolis, wings, salads and classic desserts like cannoli and New York cheesecake fill out the menu. The dough is made fresh daily, and the mozzarella comes from Wisconsin. Staff members serve with a friendly edge that fits the River District vibe. Whether you’re stopping by for lunch or a late-night slice, you’ll find filling portions and familiar flavors.
Pizza D-LUX
Tucked into a strip mall, Pizza D-LUX offers classic New York-style pizza with a side of sports memorabilia. The interior features framed jerseys and a shrine to the New York Giants, creating a casual, family-friendly atmosphere. At lunch, the two-slice special includes a drink for under ten dollars, drawing in office workers and students.
Each slice sports a thin, flexible crust with a lightly sweet edge and charred bottom spots. Customers can choose toppings such as pepperoni, sausage, mushrooms, and banana peppers, or step up to a Sicilian square with dollops of ricotta. The garlic knots and garlic bread share top billing and are often ordered by the dozen.
Seating is limited, so patrons may take their orders to go or wait at the counter. The service is fast, and the prices stay low enough to keep customers coming back. With straightforward menu choices and quick counter service, Pizza D-LUX delivers an authentic Northeast pizzeria experience without leaving Fort Myers.
Blue Moon Pizza of Ft. Myers
Blue Moon Pizza in Ft. Myers takes dough seriously, hand-stretching each crust and brushing it with olive oil before baking. You can choose a classic thin crust or a thicker Grandma’s Sicilian style. Among their standouts are the signature Meteor pie and BBQ Chicken pizza, but custom creations shine too—pick from a full roster of toppings. Gluten-free diners will find a dedicated crust option.
Inside the College Parkway plaza location, up to 100 guests enjoy an industrial-chic dining room. An outdoor patio offers additional seating when weather permits. Early evenings fill with families, sports fans gather at the bar for drafts, and late-night visitors grab slices on the go.
Take-n-bake orders let you finish cooking at home, delivering that fresh-baked aroma straight from your oven. Prices stay wallet-friendly for a family meal. The menu also features desserts and cocktails for anyone who wants more than pizza.
Nino’s Pizzeria and Restaurant
Nino’s Pizzeria and Restaurant carries on classic neighborhood Italian flavors along South Tamiami Trail with a straightforward old-school menu. The pizza lineup includes both authentic thin New York style crust and a fluffy Sicilian version. The “Nino Pizza” tops every available meat, while the “Diavola” adds jalapeños for a spicy twist. Build-your-own pies are a breeze thanks to more than twenty toppings.
Beyond pizza, the menu features garlic rolls, fried calamari, rigatoni alla vodka and calzones that rival footballs in size. Don’t skip dessert—fans race to claim a slice of lemon cello cake.
The dining room is casual and family-friendly, with space for kids and room to unwind after any busy day. A full bar serves cocktails and draft beers, and happy hour brings a lively but still conversational crowd. Moderate prices and ample parking make this strip-mall spot easy to visit. Even lobster-stuffed mushrooms sound upscale here, though the overall vibe stays comfortably familiar and reliably satisfying.
Pizza Pub Italian Restaurant And Pizzeria
Nestled in Myerlee Square Shopping Center, Pizza Pub Italian Restaurant And Pizzeria has served Fort Myers families since 1989. This no-frills spot offers New York-style pies made with dough prepared fresh each morning. Patrons can choose thin, foldable slices or go for a thick pan pizza, even a deep-dish option for a hearty meal.
Lunch slices cost three dollars, making the daily specials popular with locals. Available toppings range from classic pepperoni and sausage to roasted red peppers, artichokes, and ricotta. Brave diners can add anchovies. Specialty pizzas include Chicken Parmesan and Margherita crowned with fresh basil.
Besides pizza, the menu lists baked shells, pasta dishes, heroes, and salads. The dining room features simple tables and chairs where flip-flops blend right in. Beer and wine are available, though you won’t find a cocktail menu. Takeout and delivery services handle orders quickly, ensuring the neighborhood never goes without its favorite pie. Family-owned for decades, Pizza Pub Italian Restaurant And Pizzeria sticks to straightforward Italian comfort food and wallet-friendly prices.
